Overlooked Symptoms of High Blood Sugar (Hyperglycemia)

13 Sep 2025

Overlooked Symptoms of High Blood Sugar (Hyperglycemia)

High blood sugar, or hyperglycemia, occurs when your blood contains too much glucose. It's a common problem for individuals with diabetes, but it can also affect people without a prior diagnosis. While many are aware of the classic symptoms like increased thirst and frequent urination, numerous overlooked symptoms can signal that your blood sugar levels are too high. Recognizing these subtle signs early can prevent serious health complications.

Often, the typical signs of high blood sugar get all the attention, leaving individuals unaware of other critical indicators. For example, chronic fatigue isn't always associated with blood sugar, yet it's a common experience for those with hyperglycemia. Identifying these overlooked signs is crucial because prolonged high blood sugar can damage blood vessels, nerves, and organs. This can lead to severe conditions such as heart disease, kidney disease, and vision problems. What Do My Postprandial Blood Sugar Numbers Really Mean

Here’s why understanding the full spectrum of hyperglycemia symptoms matters:

  • Early intervention: Recognizing symptoms early allows for prompt management, preventing long-term damage.
  • Improved quality of life: Controlling blood sugar reduces debilitating symptoms, improving daily functioning and overall well-being.
  • Prevention of complications: Timely management helps stave off severe health issues linked to chronic hyperglycemia.

| Symptom | Description | Why It's Overlooked | | ---------------- | ----------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------- | | Frequent Infections | Recurring bladder infections, yeast infections, or skin infections that are slow to heal. | Often attributed to poor hygiene or other unrelated factors. | | Blurred Vision | Fluctuating vision, not just consistent blurriness. | Can be confused with needing new glasses or age-related vision changes. | | Skin Issues | Dry, itchy skin or dark patches in skin folds (acanthosis nigricans). | Mistaken for eczema, psoriasis, or normal skin conditions. | | Fatigue | Persistent tiredness, even after adequate rest. | Commonly linked to stress, lack of sleep, or other lifestyle factors. |


Subtle Skin Changes: More Than Just a Rash

Skin manifestations of hyperglycemia are frequently overlooked but can provide valuable clues. High blood sugar can affect the skin's ability to retain moisture and repair itself, leading to several noticeable issues.

  • Dry, Itchy Skin: Elevated glucose levels can pull moisture from the skin, resulting in dryness and persistent itching. This dryness can lead to cracks in the skin, creating entry points for bacteria and increasing the risk of infection.
  • Acanthosis Nigricans: This condition is characterized by dark, velvety patches that typically appear in skin folds such as the neck, armpits, or groin. It is often a sign of insulin resistance, which is closely linked to high blood sugar levels.
  • Skin Tags: Small, benign growths that often appear on the neck, armpits, or eyelids. They are common in people with insulin resistance and high blood sugar.
  • Slow-Healing Cuts and Sores: Hyperglycemia impairs the body's ability to heal, leading to prolonged healing times for cuts, scrapes, and sores. This increases the risk of infection and complications.
  • Diabetic Dermopathy: This condition presents as small, oval, and slightly raised patches on the lower legs. They are caused by changes in the small blood vessels that supply the skin.

Case Study: A 45-year-old woman noticed dark patches on her neck but assumed it was a tanning issue. During a routine checkup, her doctor recognized acanthosis nigricans and ordered a blood sugar test, revealing she had prediabetes. Early intervention with diet and exercise helped her manage her blood sugar levels and prevent the onset of full-blown diabetes.

| Skin Symptom | Explanation | Actionable Step | | ---------------------- | --------------------------------------------------------------------------- | ------------------------------------------------------------------------------ | | Dry, Itchy Skin | High blood sugar draws moisture from the skin. | Use a fragrance-free, hypoallergenic moisturizer regularly. | | Acanthosis Nigricans | Sign of insulin resistance. | Consult a doctor for blood sugar testing and potential lifestyle modifications. | | Slow-Healing Wounds | Hyperglycemia impairs healing. | Keep wounds clean and covered; seek medical attention if they don't heal quickly. | A Practical Guide To Mastering Your Blood Sugar Management


Unexplained Fatigue and Cognitive Issues

While fatigue and cognitive issues are common complaints in modern life, they can also be silent indicators of hyperglycemia. When blood sugar levels are consistently high, they can interfere with the body's energy production and brain function.

  • Persistent Fatigue: High blood sugar can hinder the body's ability to effectively use glucose for energy, leading to persistent tiredness even after adequate rest. This fatigue can be debilitating and significantly impact daily activities.
  • Brain Fog: Many people with hyperglycemia report experiencing "brain fog," characterized by difficulty concentrating, memory problems, and mental sluggishness. This is due to the brain not receiving a steady supply of glucose, its primary fuel.
  • Irritability: Fluctuations in blood sugar levels can affect mood and lead to increased irritability, anxiety, or even symptoms of depression. Maintaining stable blood sugar is crucial for emotional well-being.
  • Difficulty with Focus and Concentration: Elevated blood sugar levels can impair cognitive function, making it harder to focus on tasks, make decisions, and solve problems.

Practical Example: A schoolteacher noticed she was struggling to remember students' names and felt constantly exhausted despite getting enough sleep. Her doctor checked her blood sugar levels, revealing she had type 2 diabetes. By managing her blood sugar with medication and lifestyle changes, her energy levels improved, and her cognitive function returned.

  • Research: A study published in the "Journal of Diabetes Science and Technology" found that individuals with poorly controlled blood sugar had significantly lower cognitive performance compared to those with well-managed levels. The research highlighted the impact of hyperglycemia on brain health and the importance of maintaining stable glucose levels.

| Cognitive Symptom | Possible Cause | Recommended Action | | ----------------------- | --------------------------------------------------------------------- | ---------------------------------------------------------------------------------- | | Persistent Fatigue | Inefficient use of glucose for energy. | Monitor blood sugar levels and discuss management options with a healthcare provider. | | Brain Fog | Lack of steady glucose supply to the brain. | Eat balanced meals with complex carbohydrates to maintain stable blood sugar. | | Irritability | Fluctuations in blood sugar levels. | Engage in regular physical activity and stress-reducing activities. |


Unusual Thirst and Frequent Urination: Beyond the Obvious

Increased thirst and frequent urination are classic signs of hyperglycemia, but understanding the underlying mechanisms can help you recognize when these symptoms are more than just ordinary discomfort.

  • Excessive Thirst (Polydipsia): When blood sugar levels are high, the body tries to dilute the excess glucose by drawing water from the cells, leading to dehydration and intense thirst. This thirst is often unquenchable, even after drinking large amounts of fluid.
  • Frequent Urination (Polyuria): As the kidneys attempt to filter out excess glucose from the blood, they produce more urine, leading to frequent trips to the bathroom, especially at night (nocturia).
  • Dehydration Symptoms: Beyond just thirst, hyperglycemia-induced dehydration can manifest as dry mouth, dizziness, lightheadedness, and decreased skin elasticity.

Quantifiable Insight: Studies show that uncontrolled hyperglycemia can increase urine output by as much as 5-10 liters per day. This excessive fluid loss can lead to significant electrolyte imbalances and contribute to other health issues.

| Symptom | Explanation | Immediate Action | | --------------------- | ------------------------------------------------------------------ | ------------------------------------------------------------- | | Excessive Thirst | Body's attempt to dilute high glucose levels. | Drink water, but monitor fluid intake and consult a doctor. | | Frequent Urination | Kidneys filtering out excess glucose. | Avoid sugary drinks and consult a healthcare professional. | | Dehydration Symptoms | Fluid loss due to hyperglycemia. | Rehydrate with water and seek medical advice. |


Frequently Recurring Infections

High blood sugar levels can weaken the immune system, making individuals more susceptible to infections. These infections can manifest in various forms and often recur despite treatment.

  • Yeast Infections: Elevated glucose levels create an ideal environment for yeast to thrive, leading to vaginal yeast infections in women and balanitis (inflammation of the foreskin) in men.
  • Bladder Infections (UTIs): High blood sugar can impair the function of white blood cells, which are essential for fighting off infections. This makes it easier for bacteria to multiply in the urinary tract, leading to recurrent UTIs.
  • Skin Infections: People with hyperglycemia are more prone to skin infections like cellulitis, folliculitis, and carbuncles. These infections can be more severe and take longer to heal due to impaired immune function.

Real-world example: A young woman who struggled with consistent Yeast infection symptoms even after prescribed medication, find out that the cause was high blood sugar after an anual consultation with her doctor. Diet control, good hygiene and medicine helped overcome the condition

| Infection Type | Explanation | Prevention Tip | | ----------------- | ----------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | | Yeast Infections | Elevated glucose levels promote yeast growth. | Maintain good hygiene, wear breathable clothing, and consider probiotic supplements. | | Bladder Infections | Impaired white blood cell function. | Stay hydrated, practice good hygiene, and empty your bladder regularly. | | Skin Infections | High blood sugar impairs the body's ability to fight off infections and heal wounds. | Keep skin clean and moisturized, avoid scratching, and seek medical attention for any cuts or wounds that don't heal quickly. | The Ultimate Food List To Lower Your A1C Blood Sugar


How to Manage High Blood Sugar and Prevent Complications

Recognizing overlooked symptoms of hyperglycemia is just the first step. Taking proactive measures to manage blood sugar levels can help prevent serious complications and improve overall quality of life.

  • Regular Blood Sugar Monitoring: Use a blood glucose meter or continuous glucose monitor (CGM) to track your blood sugar levels regularly. This will help you understand how your body responds to different foods, activities, and medications.
  • Dietary Modifications: Follow a balanced diet that is low in sugar, refined carbohydrates, and saturated fats. Focus on consuming whole grains, lean proteins, fruits, and vegetables.
  • Regular Physical Activity: Engage in at least 30 minutes of moderate-intensity exercise most days of the week. Physical activity helps improve insulin sensitivity and lower blood sugar levels.
  • Medication Adherence: If you have been prescribed medication for diabetes or hyperglycemia, take it as directed by your healthcare provider. Don't skip doses or change the dosage without consulting your doctor.
  • Regular Checkups: Schedule regular checkups with your doctor to monitor your blood sugar levels, screen for complications, and make any necessary adjustments to your treatment plan.

Pro-tip: Keep a journal of your food intake, physical activity, and blood sugar readings. This information can help you identify patterns and make informed decisions about managing your hyperglycemia.

By Adrian Vella, M.D.