Mistakes to Avoid: 5 Surprising Factors Affecting Your Blood Sugar Levels
13 Sep 2025Mistakes to Avoid: 5 Surprising Factors Affecting Your Blood Sugar Levels
Managing your blood sugar levels can feel like a constant balancing act. You likely already know the basics, like watching your carbohydrate intake and staying active. However, there are several less-obvious factors that can significantly impact your glucose levels, often leading to unexpected spikes or drops. Avoiding these common mistakes can make a huge difference in your overall health and well-being. Let's dive into five surprising factors affecting your blood sugar and what you can do about them.
1. Sleep Deprivation: More Than Just Feeling Tired
We all know sleep is essential, but did you realize how crucial it is for blood sugar control? When you're sleep-deprived, your body becomes more insulin resistant. Insulin resistance means your cells don't respond as well to insulin, forcing your pancreas to produce more insulin to compensate. Over time, this can lead to elevated blood sugar levels.
Chronic sleep deprivation also affects the hormones that regulate appetite, specifically increasing levels of ghrelin (the hunger hormone) and decreasing levels of leptin (the satiety hormone). This hormonal imbalance can lead to increased cravings for sugary and processed foods, which further exacerbate blood sugar fluctuations.
What to do about it: Aim for 7-9 hours of quality sleep each night. Establish a regular sleep schedule, create a relaxing bedtime routine, and ensure your bedroom is dark, quiet, and cool. If you have trouble sleeping, consult with your doctor to rule out any underlying sleep disorders like sleep apnea. The Best Breakfasts To Avoid A Mid Morning Blood Sugar Crash
2. Dehydration: Water's Role in Glucose Metabolism
Staying hydrated is crucial for overall health, but it's often overlooked when considering blood sugar management. When you're dehydrated, your blood becomes more concentrated, leading to a higher glucose concentration. This is because there is less fluid volume to dilute the glucose in your bloodstream.
Dehydration also impacts kidney function. Your kidneys play a vital role in filtering excess glucose from your blood and excreting it in urine. When you're dehydrated, your kidneys have to work harder, and their efficiency in filtering glucose may be reduced, leading to higher blood sugar levels.
What to do about it: Drink plenty of water throughout the day. Aim for at least 8 glasses (64 ounces) daily, and even more if you're physically active or live in a hot climate. Monitor the color of your urine; it should be pale yellow to clear. Avoid sugary drinks like sodas and juices, which can contribute to dehydration and worsen blood sugar control.
3. Stress: The Silent Blood Sugar Spike Trigger
Stress is a pervasive part of modern life, but its impact on blood sugar is often underestimated. When you're stressed, your body releases stress hormones like cortisol and adrenaline. These hormones trigger the release of glucose from your liver to provide you with quick energy. This surge of glucose can lead to a significant spike in your blood sugar levels.
Chronic stress can also lead to insulin resistance. Constant exposure to stress hormones can desensitize your cells to insulin, making it harder for glucose to enter your cells and be used for energy. This can result in persistently elevated blood sugar levels and an increased risk of developing type 2 diabetes. Common Mistakes That Sabotage Your Blood Sugar And Weight Loss
What to do about it: Practice stress-reduction techniques such as meditation, yoga, deep breathing exercises, or spending time in nature. Regular physical activity can also help lower stress hormones and improve insulin sensitivity. Identify your stress triggers and develop coping strategies to manage them effectively. Consider talking to a therapist or counselor if you're struggling to manage your stress on your own.
4. Artificial Sweeteners: A Sweet Deception?
Many people turn to artificial sweeteners as a sugar substitute to help manage their blood sugar levels and lose weight. However, some research suggests that artificial sweeteners may not be as beneficial as once thought and could potentially have negative effects on glucose metabolism. How To Improve Your Fasting Blood Sugar A Step By Step Guide
While artificial sweeteners don't directly raise blood sugar levels like regular sugar, they may indirectly affect them by altering the gut microbiome. Some studies suggest that artificial sweeteners can disrupt the balance of bacteria in the gut, leading to impaired glucose tolerance and insulin resistance. Additionally, some people report experiencing increased cravings for sugary foods after consuming artificial sweeteners.
What to do about it: Be mindful of your intake of artificial sweeteners. Consider using natural sweeteners like stevia or monk fruit in moderation. Focus on reducing your overall consumption of sweet-tasting foods and beverages, regardless of whether they contain sugar or artificial sweeteners. Pay attention to how your body responds to different artificial sweeteners and choose options that don't negatively impact your blood sugar or cravings.
5. Certain Medications: A Hidden Culprit
Certain medications can inadvertently affect blood sugar levels. While many people are aware that corticosteroids like prednisone can raise blood sugar, other medications can also have a similar effect. These include certain diuretics, antidepressants, decongestants, and beta-blockers.
These medications can interfere with insulin production, insulin sensitivity, or glucose metabolism, leading to elevated blood sugar levels. It's important to be aware of the potential side effects of any medications you're taking and to discuss any concerns with your doctor.
What to do about it: Talk to your doctor or pharmacist about all the medications you're taking, including prescription drugs, over-the-counter medications, and herbal supplements. Ask about the potential impact of these medications on your blood sugar levels. If you notice significant changes in your blood sugar after starting a new medication, contact your doctor immediately. Your doctor may need to adjust your medication dosage or recommend alternative treatments to better manage your blood sugar.
Understanding The Impact on Key Blood Sugar Metrics

Different factors have various impacts on metrics that help track blood sugar. The following table gives an overview of potential impacts from the issues previously discussed.
Factor | Impact on Fasting Blood Sugar | Impact on HbA1c | Potential Outcomes |
---|---|---|---|
Sleep Deprivation | Increases | Increases over time | Increased insulin resistance, higher long-term glucose levels |
Dehydration | Increases | Potentially increases if chronic | Concentrated blood glucose, kidney strain |
Stress | Increases significantly | Increases if prolonged | Release of glucose from the liver, insulin resistance |
Artificial Sweeteners | May not directly increase | Potentially increases if alters gut microbiome | Possible disruption of gut flora, increased cravings |
Certain Medications | Varies depending on medication | Potentially increases depending on medication and duration | Medication side effects interfere with glucose metabolism or insulin function |
Conclusion: Taking a Holistic Approach to Blood Sugar Control
Managing blood sugar levels effectively involves more than just diet and exercise. By being aware of these five surprising factors—sleep deprivation, dehydration, stress, artificial sweeteners, and certain medications—and taking steps to address them, you can gain better control over your glucose levels and improve your overall health. Remember to consult with your healthcare provider for personalized advice and guidance on managing your blood sugar.
By Christopher T. Pullins, M.D.