How To Avoid Insulin Resistance And Why It's Important | Dr. Robert Lustig & Dr. Dom D'Agostino [65b868]

2025-09-13

Hypoglycemia: What Should I Do Right Away?

Hypoglycemia, often referred to as low blood sugar, is a condition that occurs when the level of glucose (sugar) in your blood drops below normal. This can happen to anyone, but it's especially common in people with diabetes, particularly those who take insulin or certain oral medications. Recognizing the symptoms and knowing how to act quickly can prevent serious complications. This article will delve into the immediate steps you should take when experiencing hypoglycemia, emphasizing the importance of swift action.

Why Immediate Action Matters The brain relies heavily on glucose as its primary source of energy. When blood sugar levels plummet, the brain doesn’t get the fuel it needs, leading to various symptoms. If left unaddressed, hypoglycemia can progress to more severe states, potentially causing confusion, seizures, loss of consciousness, or even coma. Quick intervention is not just advisable—it's crucial to safeguard your well-being.

Recognizing the Symptoms Being able to recognize the early signs of hypoglycemia is the first step in responding appropriately. Common symptoms can vary from person to person but often include:

  • Shakiness or Trembling: Your hands might tremble, and your whole body might feel shaky.
  • Sweating: Unexplained sweating, even if you’re not hot.
  • Dizziness or Lightheadedness: Feeling like the room is spinning or like you might faint.
  • Confusion or Difficulty Concentrating: You might have trouble thinking clearly or focusing on tasks.
  • Rapid Heartbeat: Your heart may feel like it’s racing.
  • Hunger: Sudden, intense hunger even if you ate recently.
  • Anxiety or Irritability: Feeling on edge or more easily agitated than usual.
  • Pale Skin: Noticeably paler than normal.
  • Tingling or Numbness: Especially around the lips or fingers.

It's essential to be mindful of these signals and react quickly, especially if you're diabetic or prone to experiencing hypoglycemia.


The 15-15 Rule: A Fast and Effective Approach

When you suspect you're having a hypoglycemic episode, a standardized approach called the 15-15 rule is your go-to strategy. This method is designed to raise your blood sugar levels quickly and effectively. Here’s a detailed breakdown of how to apply the rule:

  1. Check Your Blood Sugar (If Possible): If you have a blood glucose meter available, check your blood sugar level immediately. If it reads below 70 mg/dL (3.9 mmol/L), it's highly likely that you are experiencing hypoglycemia. However, if you recognize the symptoms and cannot check, don't delay treatment.

  2. Consume 15 Grams of Fast-Acting Carbohydrates: Once you've confirmed low blood sugar (or suspect it based on symptoms), take in 15 grams of a quick source of carbohydrates. These types of sugars are easily digested and rapidly enter the bloodstream. Ideal options include:

    • Glucose Tablets: 3-4 tablets, depending on their strength. These are readily available at pharmacies and are often the fastest way to boost blood sugar.
    • Glucose Gel: One small packet can often provide the necessary 15 grams. These are easily portable.
    • Fruit Juice: ½ cup (about 4 ounces or 120 ml) of juice that contains sugar, such as orange, apple, or grape. Ensure it’s not a “diet” or sugar-free variety.
    • Regular Soda: ½ can of a non-diet soda (such as Coca-Cola, Sprite or similar). Do not use sugar-free options.
    • Hard Candies: 4-5 hard candies that you can chew and swallow quickly.
    • Honey or Sugar: 1 tablespoon of sugar or honey can be a temporary option when others are not available. Be aware that these may take slightly longer to absorb.
    Source Amount Approximate Carbohydrates (g) Speed of Absorption
    Glucose Tablets 3-4 15 Very Fast
    Glucose Gel 1 packet 15 Very Fast
    Fruit Juice (regular) ½ cup (4 oz / 120 ml) 15 Fast
    Regular Soda ½ can 15 Fast
    Hard Candies 4-5 15 Moderate
    Honey/Sugar 1 tablespoon 15 Slower Compared to Others
  3. Wait 15 Minutes: Once you have consumed your chosen source of tea and blood sugar levels carbohydrates, wait for 15 minutes. This allows your body time to absorb the sugar and elevate your blood glucose level. Avoid the urge to eat more immediately.

  4. Recheck Your Blood Sugar (If Possible): After 15 minutes, if you have a blood glucose meter, check your blood sugar again. If blood sugar 159 after meal it's still below 70 mg/dL or you're still experiencing symptoms, repeat the process (step 2). If it is at or above that level and symptoms are resolved, continue with step 5.

  5. Have a More Substantial Snack or Meal: Once your blood sugar has improved, have a more substantial meal or snack to stabilize your blood sugar. Options should include some protein, healthy fat, and complex carbohydrates, such as:

    • A slice of whole grain toast with peanut butter.
    • A handful of almonds with a piece of fruit.
    • A small container of yogurt with granola.

What to Do If Symptoms Persist or Worsen

While the 15-15 rule is generally effective, sometimes symptoms might not resolve or could even get worse. In these instances, additional steps and precautions blood sugar 120 mg dl are needed:

  1. If Symptoms Worsen: If after applying the 15-15 rule your symptoms become more severe (significant confusion, loss of consciousness, or seizure), it’s crucial to seek immediate medical attention. Do not hesitate to call emergency services. Someone in that situation will likely require glucagon or IV glucose treatment from healthcare professionals.

  2. Glucagon Kit: If you or a loved one has a history of severe hypoglycemia, consider obtaining a prescription for glucagon. Glucagon is a hormone that raises blood sugar and can be administered via injection or a nasal spray when someone is unable to take anything by mouth. Make sure you and your family or friends know how to use a glucagon kit.

  3. When the Person is Unconscious: If someone is unconscious due to hypoglycemia, do not give them anything to eat or drink. Instead, administer glucagon if it's available, and call emergency services right away.

  4. Medical Alert Identification: Always wear a medical alert bracelet or necklace if you have diabetes or are prone to hypoglycemia. This can notify medical personnel of your condition in case of an emergency.

  5. See your doctor: If you frequently experience hypoglycemia, or notice a new pattern with low blood sugar, you should see your primary care provider to review your health and treatment plans to ensure they meet your needs. They may need to make adjustments. It is also important to see them after you experience severe hypoglycemia.

Key Takeaway:

Understanding the symptoms of hypoglycemia and acting quickly using the 15-15 rule can be life-saving. Prompt recognition and effective action will help to ensure you regain stable blood sugar and prevent severe complications. Knowing when to seek medical help is crucial. Educating yourself and having plans in place can provide comfort, safety and better health.

Insulin resistance is when cells stop responding to insulin’s signal to uptake glucose. It’s a hallmark of prediabetes, Type 2 diabetes, and other forms of metabolic dysfunction, and it manifests as several chronic disease, ranging from Alzheimer’s to polycystic ovarian syndrome. Dr. Robert Lustig and Dr. Dominic D’Agostino discuss the importance of monitoring insulin levels, why a high or increasing insulin level is a problem, and how insulin resistance hinders weight management. Sign Up to Get Your Ultimate Guide to Glucose: 00:00 — Intro 01:44 — What is insulin? 04:43 — What is insulin resistance? 15:50 — There are three types of insulin resistance 36:03 — Weight management is not about calories in and calories out 44:00 — Adding more insulin to the equation of Type 2 diabetes isn’t necessarily the answer 49:31 — Insulin is a crucial biomarker to measure for metabolic health 52:11 — Insulin resistance is a hinderance to weight management 54:42 — The intake of too much leucine can lead to insulin resistance 1:00:22 — Fiber feeds the gut microbiome and is crucial for metabolic health 1:11:27 — Is intermittent fasting necessary? 👋 WHO WE ARE: Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life. 🔗 LINKS: Transcripts & Show notes: Subscribe here on YouTube: Connect with Robert Lustig, MD, on Instagram: Connect with Robert Lustig, MD, on Twitter: Connect with Dominic D’Agostino, PhD, on Instagram: Connect with Dominic D’Agostino, PhD on Twitter:
How to Avoid Insulin Resistance and Why it's Important | Dr. Robert Lustig & Dr. Dom D'Agostino